| Time | Schedule |
|---|---|
| 9:30 - 11:00 am | Welcome & Registration (Breakfast) |
|
INAUGURAL FUNCTION |
11.00 - 1.00 pm |
Welcome address by Meeting Secretary (Dr. Indrajit Sahu, SRMIST)
A short video clip about SRM-IST --Lighting of the lamp-- Special address: Prof. LS Shashidhara, Director, National Centre of Biological Sciences, Bangalore Inaugural address: Lt Col Dr. A Ravi Kumar, Pro-Vice Chancellor, SRM Medical College & Hospital Keynote address: C. Muthamizhchelvan, Vice Chancellor, SRM-IST University, Chennai Presidential address: Dr. P Satyanarayan, President, SRM-IST University, Chennai A short video clip about Prof. Aaron Ciechanover (8 min) Felicitation to Prof. Aaron Ciechanover Speech by Prof. Aaron Ciechanover (20 min) Title: The discovery of the ubiquitin system – how embarrassingly simple it was. Vote of thanks: Dr. Rajiv Janardhanan (Conference Chairperson) |
| 1:00 - 2.00 pm | Networking and Lunch |
| Session-1 | UBIQUITIN SIGNALING Chair- Dr. Ranabir Das NCBS Bangalore |
| 2.00 - 2.30 pm |
Invited Talk - 1 Prof. David Komander, WEHI, Australia Title: Crossing Codes – at the intersection between ubiquitin and sugars |
| 2.30 - 3.00 pm |
Invited Talk - 2 Prof. Yogesh Kulathu,MRC-PPU, University of Dundee Title: Regulation of cellular stress responses by branched ubiquitin signalling. |
| 3.00 - 3.30 pm |
Invited Talk - 3 Dr. Maddika Subba Reddy, CDFD Hyderabad Title:Canonical vs non-canonical ubiquitination: control of protein fate. |
| 3.30 - 4.00 pm |
Short talks (10 minutes) by young Researchers (On the 3 themes) - Ubiquitin signalling - Ubiquitination, Deubiquitination & Ub-like modifications - Proteostasis & Protein degradation pathways Selected Talk – 1: TBA Selected Talk - 2: TBA Selected Talk - 3: TBA |
| 4.00 - 4:30 pm | Networking and Coffee break (Poster installation) |
| Session-2 |
Ubiquitin signaling Chair- Dr. Muralidhara Rao Maradana, SRMIST, Chennai, India |
| 4.30 - 5.00 pm |
Invited Talk - 4 Prof. Kazuhiro Iwai,Kyoto University, Japan Title: Ubiquitin in signaling: a tale of atypical linear ubiquitin chains |
| 4.30 - 5.00 pm |
Invited Talk - 5 Dr. Parul Mishra,University of Hyderabad, India Title: Decoding the ubiquitin code complexity: From cellular harmony to disease phenotype |
| 5.30 - 6.00 pm |
Invited Talk - 6 Prof. Ashraf Brik,Technion-IIT, Haifa, Israel Title: NNovel approaches to modulate ubiquitin signaling: Chemistry and Biology |
| 6.00 - 6.20 pm |
4 Flash-talks of 3 minutes each from young-researchers Themes : Ubiquitin signalling; Ubiquitination, Deubiquitination & Ub-like modifications; Proteostasis & Protein degradation pathways. |
| 6.20 - 8.00 pm |
Networking & POSTER SESSION – 1 (Coordinators: Dr. Dhruv Nandi & Dr. A. Preethika) Themes : Ubiquitin signalling; Ubiquitination, Deubiquitination & Ub-like modifications; Proteostasis & Protein degradation pathways. |
| 7:30 - 9:30 pm | Dinner |
| Time | Schedule |
|---|---|
| 8.00 - 9.00 am | Breakfast |
| Session-3 | Structure & Function of UPS CHAIR- Dr. Senthil Thangaraj, SRMIST, Chennai, India |
| 9.00 - 9.30 am | Invited Talk - 7 Prof. Christopher Lima,MSKCC, New York US Title: Capturing conformational transitions in the ubiquitin conjugation cascade |
| 9.30 - 10.00 am | Invited Talk - 8 Dr. Atul Kumar, IISER, Bhopal Title: : New insights into the activation mechanism of Parkin E3-ligase |
| 10.00- 11.00 am | Plenary Lecture by Noble Laureate Prof. Aaron Ciechanover, Technion-IIT, Haifa, Israel Title: Control of nucleo-cytosolic proteasomal translocation as a platform for anti-cancer drug development. |
| 11.00 - 11.30 am | Networking and Coffee break |
| Session-4 | Structure & Function of UPS CHAIR-Dr. Shiny PJ, SRMIST, Chennai, India |
| 11.30 - 12.00 pm | Invited Talk - 9 Dr. Sonja Lorenz,MPI Gottingen Title: Regulatory concepts in HECT-type ubiquitin ligases |
| 12:00 - 12.30 pm | Invited Talk - 10, Dr. Ranabir Das, NCBS, Bangalore Title: NMR-detected protein dynamics is present at the centre of host-pathogen interactions |
| 12.30 - 1.00 pm | Short talks (10 min) by young Researchers- - (On the 3 themes)
- Structure & function of Ubiquitin-Proteasome System (UPS) - UPS role in Human health & diseases - UPS in Cancer & Neurodegeneration Selected Talk - 4: TBA Selected Talk - 5: TBA Selected Talk - 6: TBA |
| 1:00 - 2.00 pm | Networking and Lunch (Poster installation) |
| Session-5 |
Proteostasis & Protein degradation pathways Chair- Dr. Madhumitha Haridoss, SRMIST, Chennai, India |
| 2.00 - 2.30 pm | Invited Talk - 11 Dr. Carlos Castaneda,Syracuse University, New York, USA Title: Role of ubiquitin-binding shuttle protein phase transitions in protein quality control |
| 2:30 - 3.00 pm | Invited Talk - 12 Dr. Shravan Kumar Mishra,IISER Mohali Title: Nucleus-to-Golgi signalling through Sde2-specific deubiquitination enzymes |
| 3:00 - 3.30 pm |
6 Flash-talks of 3 minutes each from young-researchers Themes : Structure & function of Ubiquitin-Proteasome System (UPS); UPS role in Human health & diseases; UPS in Cancer & Neurodegeneration; |
| 3.30 - 4:00 pm | Networking and Coffee break |
| 3:30 - 5.00 pm |
POSTER SESSION – 2 (Coordinators: Dr. Piyush Agrawal & Dr. P. Venketaraman) Themes : Structure & function of Ubiquitin-Proteasome System (UPS); UPS role in Human health & diseases; UPS in cancer & neurodegeneration. |
| Session-6 |
Drug discovery in UPS Chair- Dr. Gisha Sivan, SRMIST, Chennai, India |
| 5.00 - 5:30 pm | Invited Talk - 13 Prof. T. P. Singh,AIIMS, New Delhi, India Title: Structure-based rational approaches for new drug discovery |
| 5.30 - 6:00 pm | Short talks (10 min) by young Researchers- - (On the 3 themes) - Autophagy, Mitophagy & ERAD pathways - Targeted Protein degradation & PROTACs - Drug discovery in UPS Selected Talk - 7: TBA Selected Talk - 8: TBA Selected Talk - 9: TBA |
| 6.00 - 7.00 pm |
Panel discussion: “How far are we towards drug discoveries targeting the UPS”. Moderator : Dr. Prasanna Venkatraman, Dy Director, ACTREC, Mumbai Panelists : Prof. Aaron Ciechanover, Technion-IIT, Haifa, Israel Prof. T. P. Singh, AIIMS, New Delhi, India Prof. David Komander, WEHI, Australia Prof. Christopher Lima, MSKCC, New York US |
| 7.00 - 8.00 pm | Cultural Programme |
| 8:00 - 10:00 pm | Dinner/Gala Dinner & Networking |
| Time | Schedule |
|---|---|
| 8.00 - 9.00 am | Breakfast (Poster installation) |
| Session-7 | UPS in human health & diseases CHAIR- Dr. Indrajit Sahu, SRMIST, Chennai, India |
| 9.00 - 9.30 am | Invited Talk - 14 Prof. Michael GlickmanTechnion-IIT, Haifa, Israel Title: A cryptic ligase activity and ubiquitin signaling disruption in Alzheimer's disease: Mechanistic insights and implications |
| 9.30 - 10.00 am | Invited Talk - 15 Dr. Prasanna Venkatraman, Dr. Prasanna Venkatraman Title: Proteasomal Assembly Chaperones in and out of proteostatsis |
| 10.00- 10.30 am | Invited Talk - 16 Dr. Manas Santra,NCCS, Pune Title: FBXO31 controls DNA damage repair processes by monitoring proteostasis of proteins |
| 10.30 - 11.00 am | 6 Flash-talks of 3 minutes each from young-researchers Themes: Autophagy, Mitophagy & ERAD pathways; Targeted protein degradation & PROTACs; Drug discovery in UPS. |
| 11.00 - 12.30 am |
POSTER SESSION -8 (Coordinators: Dr. Subhashis Pal & Dr. Sundaresan S) Themes : Autophagy/ Mitophagy & ERAD pathways Targeted protein degradation & PROTACs Drug discovery in UPS |
| 12.30 - 1.30 pm | Networking and Lunch |
| Session-8 | Autophagy, Mitophagy & ERAD pathways CHAIR- Dr. Raji Lenin, SRMIST, Chennai, India |
| 1.30 - 2.00 pm | Invited Talk - 17 Prof. Ivan Dikic,IBC Frankfurt, Germany Title: Ubiquitin and Autophagy networks in regulation of ER- remodelling |
| 2.00 - 2.30 pm | Invited Talk - 18 Dr. Santosh Chouhan,CCMB, Hyderabad Title: RNA-binding E3-ubiquitin ligase in Cancer and Immunity |
| 2.30 - 3.00 pm | Invited Talk - 19 Prof. Helen Walden,University of Glasgow Title: : Targeting Parkin substrates |
| 3.00 - 3.30 pm | Oral, Poster & Travel awards announcement by the organizing members - TBA Concluding Remarks & Vote of Thanks by Meeting Secretary (Dr. Indrajit Sahu & Dr. Raji Lenin) |
| 3.30 pm onwards | Goodbye… |
| 4.00 pm Onwards | Visit to Mahabalipuram (For Invited Speakers only) |